Toxic Shock does not remove poison stacks, nor does it make targets immune 5 seconds afterward. I'm not sure if it's intentional or if it's a mistake with the text that pops up when you learn it, but they do not agree with each other.
Poison damage scale is simply ridiculous.
Example: I killed Sasuke at level 20 by just running around and spamming shuriken and just keeping poison up.
The fact that damage over time abilities break the target's run momentum is just silly, fast ticking DoTs may as well be stuns. This goes for Inferno also.